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Evidence Library
prospective_cosmetic_study · 2021

Facial anti-aging treatments with soft peeling and microneedling technique

Amore R|Amuso D|Leonardi V|et al. · Applied Sciences
very_lowDOI · 10.3390/app11136068Verified
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Plain-English summary

Participants improved after a combined peeling and microneedling programme, but the study cannot show whether acetyl hexapeptide-19 contributed.

Population
Adults receiving facial anti-ageing treatment
Sample size
49
Intervention
Soft peeling containing multiple ingredients, followed by microneedling
Outcomes measured
Wrinkle appearance|Skin texture|Tolerability
Key findings
Facial appearance improved after the combined treatment; ingredient-specific efficacy was not established.
Limitations
Multi-component intervention|No peptide-isolation arm|Procedure effects confound ingredient effects|Limited generalisability
Risk of bias
High — uncontrolled or weakly controlled cosmetic intervention with substantial confounding.
Citation
Amore R|Amuso D|Leonardi V|et al. (2021). Facial anti-aging treatments with soft peeling and microneedling technique. Applied Sciences. https://doi.org/10.3390/app11136068
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