Evidence Library

• Intravenous kisspeptin 112-121 bolus does not acutely impact circulating vasopressin in humans
  Galbiati F; Plessow F; Plummer L; Campbell MB; Nazarloo S; Carter CS · 2026 · Journal of neuroendocrinology Randomized placebo controlled human pharmacology study
• Acetyl Dipeptide-31 Amide: A Novel Cosmetic Anti-Inflammatory Peptide That Demonstrates Anti-Aging, Firming, and Lifting Benefits
  Edison BL|Parsa R|Dufort M|et al. · 2025 · Journal of Drugs in Dermatology Laboratory and clinical cosmetic study
• MOTS-c Levels and Sarcopenia Risk in Chronic Peritoneal Dialysis Patients: A Pilot Study
  Zicarelli M; Greco M; Roumeliotis S; Lo Vasco ME; Dragone F; Kourtidou C · 2025 · Medicina (Kaunas, Lithuania) Observational pilot study
• EGRIFTA WR (tesamorelin) prescribing information
  U.S. Food and Drug Administration · 2025 · FDA Prescribing Information Regulatory label
• Sex-dependent increases in oxytocin levels in response to intravenous kisspeptin in humans
  Galbiati F; Plessow F; Plummer L; Campbell MB; Nazarloo S; Carter CS · 2025 · European journal of endocrinology Randomized placebo controlled human pharmacology study
• Kisspeptin and neurokinin B: roles in reproductive health
  Koysombat K; Tsoutsouki J; Patel AH; Comninos AN; Dhillo WS; Abbara A · 2025 · Physiological reviews Narrative review
• Effect of pemvidutide, a GLP-1/glucagon dual receptor agonist, on MASLD: a randomized, double-blind, placebo-controlled study
  Harrison SA, Browne SK, Suschak JJ, et al. · 2025 · Journal of Hepatology Randomized controlled trial
• Overview of Epitalon-Highly Bioactive Pineal Tetrapeptide with Promising Properties
  Araj SK; Brzezik J; Mądra-Gackowska K; Szeleszczuk Ł · 2025 · International journal of molecular sciences Narrative review
• Are We Ready to Measure Skin Permeation of Modern Antiaging GHK-Cu Tripeptide Encapsulated in Liposomes?
  Ogórek K; Nowak K; Wadych E; Ruzik L; Timerbaev AR; Matczuk M · 2025 · Molecules (Basel, Switzerland) Narrative review
• Simple meal announcements and pramlintide delivery versus carbohydrate counting in type 1 diabetes with automated fast-acting insulin aspart delivery: a randomised crossover trial in Montreal, Canada
  Cohen E; Tsoukas MA; Legault L; Vallis M; Von Oettingen JE; Palisaitis E · 2024 · The Lancet. Digital health Randomized controlled trial
• The glycyl-l-histidyl-l-lysine-Cu(2+) tripeptide complex attenuates lung inflammation and fibrosis in silicosis by targeting peroxiredoxin 6
  Bian Y; Deng M; Liu J; Li J; Zhang Q; Wang Z · 2024 · Redox biology Animal and in vitro study
• Glucagon and GLP-1 receptor dual agonist survodutide for obesity: a randomised, double-blind, placebo-controlled, dose-finding phase 2 trial
  le Roux CW, Steen O, Lucas KJ, et al. · 2024 · The Lancet Diabetes & Endocrinology Randomized controlled trial
• MOTS-c modulates skeletal muscle function by directly binding and activating CK2
  Kumagai H; Kim SJ; Miller B; Zempo H; Tanisawa K; Natsume T · 2024 · iScience In vitro cell study
• Cardiovascular and renal effects of apelin in chronic kidney disease
  Chapman FA|Nyimanu D|Maguire JJ|Davenport AP|Webb DJ|Newby DE · 2024 · Kidney International Randomized crossover study
• Effects of Kisspeptin on Sexual Brain Processing and Penile Tumescence in Men With Hypoactive Sexual Desire Disorder
  Mills EG, et al. · 2023 · JAMA Network Open Randomized crossover trial
• Triple-Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial
  Jastreboff AM, Kaplan LM, Frias JP, et al. · 2023 · New England Journal of Medicine Randomized controlled trial
• MOTS-c Functionally Prevents Metabolic Disorders
  Gao Y; Wei X; Wei P; Lu H; Zhong L; Tan J · 2023 · Metabolites Narrative review
• Mitochondrial-Encoded Peptide MOTS-c, Diabetes, and Aging-Related Diseases
  Kong BS; Lee C; Cho YM · 2023 · Diabetes & metabolism journal Narrative review
• Synergy of GHK-Cu and hyaluronic acid on collagen IV upregulation via fibroblast and ex-vivo skin tests
  Jiang F; Wu Y; Liu Z; Hong M; Huang Y · 2023 · Journal of cosmetic dermatology In vitro and ex vivo human skin study
• Thymosin β4 and Actin: Binding Modes, Biological Functions and Clinical Applications
  Ying Y; Lin C; Tao N; Hoffman RD; Shi D; Chen Z · 2023 · Current protein & peptide science Narrative review
• Effects of Kisspeptin Administration in Women With Hypoactive Sexual Desire Disorder
  Thurston L, et al. · 2022 · JAMA Network Open Randomized crossover trial
• Stress, kisspeptin, and functional hypothalamic amenorrhea
  Meczekalski B; Niwczyk O; Bala G; Szeliga A · 2022 · Current opinion in pharmacology Narrative review
• The Role of Kisspeptin in the Control of the Hypothalamic-Pituitary-Gonadal Axis and Reproduction
  Xie Q; Kang Y; Zhang C; Xie Y; Wang C; Liu J · 2022 · Frontiers in endocrinology Narrative review
• Glycyl-L-histidyl-L-lysine-Cu(2+) attenuates cigarette smoke-induced pulmonary emphysema and inflammation by reducing oxidative stress pathway
  Zhang Q; Yan L; Lu J; Zhou X · 2022 · Frontiers in molecular biosciences Animal study
• Randomized phase 2 study of ACE-083, a muscle-promoting agent, in facioscapulohumeral muscular dystrophy
  Statland JM|Campbell C|Desai U|Karam C|Díaz-Manera J|Guptill JT|Korngut L|Genge A|Tawil RN|Elman L|Joyce NC|Wagner KR|Manousakis G|Amato AA|Butterfield RJ|Shieh PB|Wicklund M|Gamez J|Bodkin C|Pestronk A|Weihl CC|Vilchez-Padilla JJ|Johnson NE|Mathews KD|Miller B|Leneus A|Fowler M|van de Rijn M|Attie KM · 2022 · Muscle & Nerve Randomized phase 2 trial
• Pramlintide for post-bariatric hypoglycaemia
  Sheehan A; Goldfine A; Bajwa M; Wolfs D; Kozuka C; Piper J · 2022 · Diabetes, obesity & metabolism Case series
• Tirzepatide Once Weekly for the Treatment of Obesity
  Jastreboff AM, Aronne LJ, Ahmad NN, et al. · 2022 · New England Journal of Medicine Randomized controlled trial
• Facial anti-aging treatments with soft peeling and microneedling technique
  Amore R|Amuso D|Leonardi V|et al. · 2021 · Applied Sciences Prospective cosmetic study
• First-in-Human Study of MANP: A Novel ANP (Atrial Natriuretic Peptide) Analog in Human Hypertension
  Chen HH|Wan SH|Iyer SR|Harty GJ|Boerrigter G|Burnett JC Jr · 2021 · Hypertension First in human trial
• Progress on the Function and Application of Thymosin β4
  Xing Y; Ye Y; Zuo H; Li Y · 2021 · Frontiers in endocrinology Narrative review
• Detection of LongR3-IGF-I, Des(1-3)-IGF-I and R3-IGF-I in blood and urine
  Mongongu C, et al. · 2021 · Drug Testing and Analysis Analytical and preclinical doping study
• Once-weekly cagrilintide for weight management in people with overweight and obesity: a multicentre, randomised, double-blind, placebo-controlled and active-controlled, dose-finding phase 2 trial
  Lau DCW, Erichsen L, Francisco AM, et al. · 2021 · The Lancet Randomized controlled trial
• Recombinant human thymosin beta-4 (rhTβ4) improved scalp condition and microbiome homeostasis in seborrheic dermatitis
  Yu R; Lin Q; Zhai Y; Mao Y; Li K; Gao Y · 2021 · Microbial biotechnology Single arm clinical study
• Effect of Bimagrumab vs Placebo on Body Fat Mass Among Adults With Type 2 Diabetes and Obesity: A Phase 2 Randomized Clinical Trial
  Heymsfield SB|Coleman LA|Miller R|Rooks DS|Laurent D|Petricoul O|Praestgaard J|Swan T|Frost M|Vitolins MZ · 2021 · JAMA Network Open Randomized phase 2 trial
• Acute endurance exercise stimulates circulating levels of mitochondrial-derived peptides in humans
  von Walden F|et al. · 2021 · Journal article indexed in PubMed Human observational exercise study
• Stable Gastric Pentadecapeptide BPC 157 and Wound Healing
  Seiwerth S, Milavic M, Vukojevic J, et al. · 2021 · Frontiers in Pharmacology Narrative review
• Effect of vasoactive intestinal polypeptide on development of migraine headaches: a randomized clinical trial
  Pellesi L|Al-Karagholi MAM|Chaudhry BA|Snellman J|Hannibal J|Amin FM|Ashina M · 2021 · JAMA Network Open Randomized clinical trial
• Once-Weekly Semaglutide in Adults with Overweight or Obesity
  Wilding JPH, Batterham RL, Calanna S, et al. · 2021 · New England Journal of Medicine Randomized controlled trial
• Usage of Synthetic Peptides in Cosmetics for Sensitive Skin
  Resende DISP|Ferreira MS|Lobo JMS|Almeida IF · 2021 · Pharmaceutics Narrative review
• A Novel Dual-Hormone Insulin-and-Pramlintide Artificial Pancreas for Type 1 Diabetes: A Randomized Controlled Crossover Trial
  Haidar A; Tsoukas MA; Bernier-Twardy S; Yale JF; Rutkowski J; Bossy A · 2020 · Diabetes care Randomized crossover trial
• Current perspective on a peptide hormone with significant therapeutic potential
  Fischer JP|Els-Heindl S|Beck-Sickinger AG · 2020 · Peptides Narrative review
• An Herbal Extract Combination (Biochanin A, Acetyl tetrapeptide-3, and Ginseng Extracts) versus 3% Minoxidil Solution for the Treatment of Androgenetic Alopecia: A 24-week, Prospective, Randomized, Triple-blind, Controlled Trial
  Lueangarun S|Panchaprateep R|Tempark T|Noppakun N · 2020 · Journal of Clinical and Aesthetic Dermatology Randomized triple blind controlled trial
• AEDG Peptide (Epitalon) Stimulates Gene Expression and Protein Synthesis during Neurogenesis: Possible Epigenetic Mechanism
  Khavinson V|Linkova N|Diatlova A|Trofimova S · 2020 · Molecules In vitro stem cell study
• Stable Gastric Pentadecapeptide BPC 157 and Wound Healing
  Sikirić P, Seiwerth S, Rucman R, et al. · 2020 · Frontiers in Pharmacology Narrative review
• From Angiotensin IV to Small Peptidemimetics Inhibiting Insulin-Regulated Aminopeptidase
  Hallberg M|Nyberg F · 2020 · Frontiers in Pharmacology Narrative review
• Novel Insights into the Protective Properties of ACTH((4-7))PGP (Semax) Peptide at the Transcriptome Level Following Cerebral Ischaemia-Reperfusion in Rats
  Filippenkov IB; Stavchansky VV; Denisova AE; Yuzhakov VV; Sevan'kaeva LE; Sudarkina OY · 2020 · Genes Animal gene expression study
• Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials
  Kingsberg SA, Clayton AH, Portman D, et al. · 2019 · Obstetrics & Gynecology Randomized controlled trial
• International Union of Basic and Clinical Pharmacology. CVII. Structure and Pharmacology of the Apelin Receptor with a Recommendation that Elabela/Toddler Is a Second Endogenous Peptide Ligand
  Read C|Fitzpatrick CM|Yang P|Kuc RE|Maguire JJ|Glen RC|Foster RE|Davenport AP · 2019 · Pharmacological Reviews Expert review
• VYLEESI (bremelanotide injection) prescribing information
  U.S. Food and Drug Administration · 2019 · FDA Prescribing Information Regulatory label
• Long-Term Safety and Efficacy of Bremelanotide for Hypoactive Sexual Desire Disorder
  Simon JA, Kingsberg SA, Shumel B, et al. · 2019 · Obstetrics & Gynecology Open label extension
• Selank, Peptide Analogue of Tuftsin, Protects Against Ethanol-Induced Memory Impairment by Regulating of BDNF Content in the Hippocampus and Prefrontal Cortex in Rats
  Kolik LG; Nadorova AV; Antipova TA; Kruglov SV; Kudrin VS; Durnev AD · 2019 · Bulletin of experimental biology and medicine Animal study
• Case report on premature hair graying treated with Melitane 5% and oral hair supplements
  Sakhiya JJ|Sakhiya DP|Patel VK|Daruwala F · 2019 · International Journal of Trichology Case report
• Thymosin beta 4 and the eye: the journey from bench to bedside
  Sosne G · 2018 · Expert opinion on biological therapy Narrative review
• The Effect of Anti-aging Peptides on Mechanical and Biological Properties of HaCaT Keratinocytes
  Kobiela T|Milner-Krawczyk M|Pasikowska-Piwko M|Bujak A|Dworakowska B|Jakubowska M · 2018 · International Journal of Peptide Research and Therapeutics In vitro cell study
• Control of Postprandial Hyperglycemia in Type 1 Diabetes by 24-Hour Fixed-Dose Coadministration of Pramlintide and Regular Human Insulin: A Randomized, Two-Way Crossover Study
  Riddle MC; Nahra R; Han J; Castle J; Hanavan K; Hompesch M · 2018 · Diabetes care Phase 1 pharmacokinetic pharmacodynamic study
• The efficacy of Semax in treatment of patients at different stages of ischemic stroke
  Gusev EI|et al. · 2018 · Zhurnal Nevrologii i Psikhiatrii imeni S.S. Korsakova Clinical rehabilitation study
• The molecular aspects of heptapeptide Selank biological activity
  Vyunova TV|et al. · 2018 · Molecular Biology Narrative review
• Semax, an analog of ACTH((4-7)), regulates expression of immune response genes during ischemic brain injury in rats
  Medvedeva EV; Dmitrieva VG; Limborska SA; Myasoedov NF; Dergunova LV · 2017 · Molecular genetics and genomics : MGG Animal gene expression study
• Peptide Selank Enhances the Effect of Diazepam in Reducing Anxiety in Unpredictable Chronic Mild Stress Conditions in Rats
  Kasian A; Kolomin T; Andreeva L; Bondarenko E; Myasoedov N; Slominsky P · 2017 · Behavioural neurology Animal combination study
• GABA, Selank, and Olanzapine Affect the Expression of Genes Involved in GABAergic Neurotransmission in IMR-32 Cells
  Filatova E; Kasian A; Kolomin T; Rybalkina E; Alieva A; Andreeva L · 2017 · Frontiers in pharmacology In vitro cell study
• Myostatin inhibitor ACE-031 treatment of ambulatory boys with Duchenne muscular dystrophy: results of a randomized, placebo-controlled clinical trial
  Campbell C, McMillan HJ, Mah JK, et al. · 2017 · Muscle and Nerve Randomized placebo controlled trial
• Kisspeptin modulates sexual and emotional brain processing in humans
  Comninos AN, et al. · 2017 · Journal of Clinical Investigation Human experimental study
• GHK-Cu-liposomes accelerate scald wound healing in mice
  Wang X, et al. · 2017 · International Journal of Nanomedicine Animal and in vitro study
• Topical peptides as cosmeceuticals
  Pai VV|Bhandari P|Shukla P · 2017 · Indian Journal of Dermatology, Venereology and Leprology Narrative review
• A single-chain derivative of the relaxin hormone is a functionally selective agonist of the G protein-coupled receptor RXFP1
  Hossain MA|Kocan M|Yao ST|Royce SG|Nair VB|Siwek C|Patil NA|Harrison IP|Rosengren KJ|Selemidis S|Summers RJ|Sasson S|Bathgate RAD|Wade JD · 2016 · Chemical Science Preclinical mechanistic study
• Cardiovascular effects of urocortin 2 and urocortin 3 in patients with chronic heart failure
  Stirrat CG|Venkatasubramanian S|Pawade T|Mitchell AJ|Shah ASV|Lang NN|Newby DE · 2016 · British Journal of Clinical Pharmacology Comparative human infusion study
• MOTS-c: A novel mitochondrial-derived peptide regulating muscle and fat metabolism
  Lee C|Kim KH|Cohen P · 2016 · Free Radical Biology and Medicine Narrative review
• Thymosin β4 Promotes Dermal Healing
  Kleinman HK, Sosne G · 2016 · Vitamins and Hormones Narrative review
• ARA 290, a nonerythropoietic peptide engineered from erythropoietin, improves metabolic control and neuropathic symptoms in patients with type 2 diabetes
  Brines M|et al. · 2015 · Molecular Medicine Phase 2 clinical study
• A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management
  Pi-Sunyer X, Astrup A, Fujioka K, et al. · 2015 · New England Journal of Medicine Randomized controlled trial
• Identification of the small research tetra peptide Epitalon, assumed to be a potential treatment for cancer, old age and Retinitis Pigmentosa in two illegal pharmaceutical preparations
  Vanhee C; Moens G; Van Hoeck E; Deconinck E; De Beer JO · 2015 · Drug testing and analysis Analytical characterization study
• Design, characterization, and first-in-human study of the vascular actions of a novel biased apelin receptor agonist
  Brame AL|Maguire JJ|Yang P|Dyson A|Torella R|Cheriyan J|Singer M|Glen RC|Wilkinson IB|Davenport AP · 2015 · Hypertension First in human study
• Effect of Intra-articular Injection of AOD9604 with or without Hyaluronic Acid in Rabbit Osteoarthritis Model
  Kwon DR; Park GY · 2015 · Annals of clinical and laboratory science Animal study
• The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance
  Lee C|et al. · 2015 · Cell Metabolism Animal and cell study
• The efficacy of peptide bioregulators of vessels in lower urinary tract symptoms and vasculogenic erectile dysfunction
  Kitachev KV|Khavinson VK|Kuznik BI · 2014 · Advances in Gerontology Small clinical study
• The peptide Semax affects the expression of genes related to the immune and vascular systems in rat brain focal ischemia
  Medvedeva EV; Dmitrieva VG; Povarova OV; Limborska SA; Skvortsova VI; Myasoedov NF; Dergunova LV · 2014 · BMC genomics Animal gene expression study
• Analytical approaches for the detection of emerging therapeutics and non-approved drugs in human doping controls
  Thevis M; Schänzer W · 2014 · Journal of pharmaceutical and biomedical analysis Analytical chemistry review
• Xenin-25 delays gastric emptying and reduces postprandial glucose levels in humans
  Chowdhury S|Reeds DN|Crimmins DL|Patterson BW|Ladenson JH|Polonsky KS|Wice BM · 2014 · Journal of Clinical Endocrinology and Metabolism Human metabolic physiology study
• Mechano-growth factor peptide, the COOH terminus of unprocessed insulin-like growth factor 1, has no apparent effect on myoblasts or primary muscle stem cells
  Fornaro M, Hinken AC, Needle S, et al. · 2014 · American Journal of Physiology-Endocrinology and Metabolism In vitro reproducibility study
• Effect of tesamorelin on visceral fat and liver fat in HIV-infected patients with abdominal fat accumulation
  Stanley TL|et al. · 2014 · JAMA Randomized controlled trial
• Mass spectrometric characterization of a biotechnologically produced full-length mechano growth factor relevant for doping controls
  Thevis M, Thomas A, Geyer H, Schänzer W · 2014 · Growth Hormone and IGF Research Analytical characterization study
• A comparison of the anxiolytic effect and tolerability of Selank and phenazepam
  Medvedev VE|et al. · 2014 · Zhurnal Nevrologii i Psikhiatrii imeni S.S. Korsakova Comparative clinical study
• Thymosin β4 enhances the healing of medial collateral ligament injury
  Xu B, et al. · 2013 · Knee Surgery, Sports Traumatology, Arthroscopy Animal study
• ARA 290 improves symptoms in patients with sarcoidosis-associated small nerve fiber loss and increases corneal nerve fiber density
  Dahan A|et al. · 2013 · Molecular Medicine Phase 2 clinical study
• Vascular effects of urocortins 2 and 3 in healthy volunteers
  Venkatasubramanian S|Grieve DJ|MacLeod KT|Webb DJ|Newby DE · 2013 · Journal of the American Heart Association Human vascular pharmacology study
• A single ascending-dose study of muscle regulator ACE-031 in healthy volunteers
  Attie KM, Borgstein NG, Yang Y, et al. · 2013 · Muscle and Nerve Randomized placebo controlled phase 1 study
• Plasma adropin levels predict endothelial dysfunction like flow-mediated dilatation in patients with type 2 diabetes mellitus
  Topuz M|Celik A|Aslantas T|Demir AK|Aydin S|Aydin S · 2013 · Journal of Investigative Medicine Observational study
• Safety and efficacy of ARA 290 in sarcoidosis patients with symptoms of small fiber neuropathy: a randomized, double-blind pilot study
  Heij L|Niesters M|Swartjes M|Hoitsma E|Drent M|Dunckley T|Hohmann A|Cerami A|Brines M|Dahan A · 2012 · Molecular Medicine Randomized double blind pilot trial
• Xenin-25 amplifies GIP-mediated insulin secretion in humans with normal and impaired glucose tolerance but not type 2 diabetes
  Wice BM|Reeds DN|Tran HD|Crimmins DL|Patterson BW|Dunai J|Wallendorf MJ|Ladenson JH|Villareal DT|Polonsky KS · 2012 · Diabetes Human metabolic physiology study
• Mechano Growth Factor E peptide, derived from an isoform of IGF-1, activates human muscle progenitor cells and induces an increase in their fusion potential at different ages
  Kandalla PK, Goldspink G, Butler-Browne G, Mouly V · 2011 · Mechanisms of Ageing and Development In vitro human cell study
• Effects of tesamorelin, a growth hormone-releasing factor, in HIV-infected patients with abdominal fat accumulation
  Falutz J|et al. · 2010 · Journal of Clinical Endocrinology and Metabolism Pooled randomized phase 3 trials
• Semax and Pro-Gly-Pro activate the transcription of neurotrophins and their receptor genes after cerebral ischemia
  Dmitrieva VG; Povarova OV; Skvortsova VI; Limborska SA; Myasoedov NF; Dergunova LV · 2010 · Cellular and molecular neurobiology Animal gene expression study
• Effects of Tesamorelin, a Growth Hormone-Releasing Factor, in HIV-Infected Patients with Abdominal Fat Accumulation: A Randomized Placebo-Controlled Trial with a Safety Extension
  Falutz J, Potvin D, Mamputu JC, et al. · 2010 · Journal of Clinical Endocrinology and Metabolism Randomized controlled trial
• Delta sleep-inducing peptide and glucocorticoid-induced leucine zipper: potential links between circadian mechanisms and obesity?
  Gimble JM; Ptitsyn AA; Goh BC; Hebert T; Yu G; Wu X · 2009 · Obesity reviews : an official journal of the International Association for the Study of Obesity Narrative review
• VPAC and PAC receptors: from ligands to function
  Dickson L|Finlayson K · 2009 · Pharmacology and Therapeutics Receptor pharmacology review
• Phase I and pharmacokinetic study of angiotensin-1-7, an endogenous antiangiogenic hormone
  Petty WJ|Miller AA|McCoy TP|Gallagher PE|Tallant EA|Torti FM · 2009 · Clinical Cancer Research Phase 1 trial
• Identification of adropin as a secreted factor linking dietary macronutrient intake with energy homeostasis and lipid metabolism
  Kumar KG|Trevaskis JL|Lam DD|Sutton GM|Koza RA|Chouljenko VN|Kousoulas KG|Rogers PM|Kesterson RA|Thearle M|Ferrante AW Jr|Mynatt RL|Burris TP|Dong JZ|Halem HA|Culler MD|Heisler LK|Stephens JM|Butler AA · 2008 · Cell Metabolism Discovery and animal study
• Efficacy and possible mechanisms of action of a new peptide anxiolytic Selank in the therapy of generalized anxiety disorders and neurasthenia
  Zozulia AA|et al. · 2008 · Zhurnal Nevrologii i Psikhiatrii imeni S.S. Korsakova Comparative clinical study
• The human tri-peptide GHK and tissue remodeling
  Pickart L, Vasquez-Soltero JM, Margolina A · 2008 · Journal of Biomaterials Science, Polymer Edition Narrative review
• Pramlintide, the synthetic analogue of amylin
  Hoogwerf BJ · 2008 · Diabetes, Metabolic Syndrome and Obesity Narrative review
• Inhalation of vasoactive intestinal peptide in pulmonary hypertension
  Leuchte HH|Baumgartner RA|Nounou ME|Vogeser M|Neurohr C|Trautnitz M|Behr J · 2008 · European Respiratory Journal Acute human inhalation study
• Urocortin 2 infusion in human heart failure
  Davis ME|Pemberton CJ|Yandle TG|Fisher S|Lainchbury JG|Frampton CM|Rademaker MT|Richards AM · 2007 · European Heart Journal Human infusion study
• Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults
  Teichman SL, Neale A, Lawrence B, Gagnon C, Castaigne JP, Frohman LA · 2006 · Journal of Clinical Endocrinology and Metabolism Randomized placebo controlled trial
• Effects of topical copper tripeptide complex on CO2 laser-resurfaced skin
  Miller TR, et al. · 2006 · Archives of Facial Plastic Surgery Controlled human study
• Natriuretic peptides: their structures, receptors, physiologic functions and therapeutic applications
  Potter LR|Abbey-Hosch S|Dickey DM · 2006 · Handbook of Experimental Pharmacology Narrative review
• Delta sleep-inducing peptide: a still unresolved riddle
  Kovalzon VM|Strekalova TV · 2006 · Journal of Neurochemistry Critical narrative review
• Growth hormone releasing peptide-2, like ghrelin, increases food intake in healthy men
  Laferrère B, Abraham C, Russell CD, Bowers CY · 2005 · Journal of Clinical Endocrinology and Metabolism Controlled human pharmacology study
• Pineal peptides restore the age-related disturbances in hormonal functions of the pineal gland and pancreas in elderly monkeys
  Goncharova ND|et al. · 2005 · Bulletin of Experimental Biology and Medicine Animal study
• AOD-9604 Metabolic
  Wilding J · 2004 · Current Opinion in Investigational Drugs Drug development review
• Urocortin-1 infusion in normal humans
  Davis ME|Pemberton CJ|Yandle TG|Lainchbury JG|Rademaker MT|Nicholls MG|Richards AM · 2004 · Journal of Clinical Endocrinology and Metabolism Placebo controlled human infusion study
• Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells
  Khavinson VK|Bondarev IE|Butyugov AA|Smirnova TD · 2003 · Bulletin of Experimental Biology and Medicine In vitro cell study
• Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice
  Anisimov VN|et al. · 2003 · Biogerontology Animal lifespan study
• Peptide Epitalon activates chromatin at the old age
  Khavinson VK|et al. · 2003 · Neuro Endocrinology Letters Laboratory cell study
• AT4 receptor is insulin-regulated membrane aminopeptidase: potential mechanisms of memory enhancement
  Albiston AL|McDowall SG|Matsacos D|Sim P|Clune E|Mustafa T|Lee J|Mendelsohn FAO|Simpson RJ|Connell JM|Chai SY · 2003 · Trends in Endocrinology and Metabolism Mechanistic review
• The effects of human GH and its lipolytic fragment AOD9604 on lipid metabolism following chronic treatment in obese mice and beta-3 adrenergic knockout mice
  Heffernan MA|et al. · 2001 · Endocrinology Animal study
• Increase of fat oxidation and weight loss in obese mice caused by chronic treatment with human growth hormone or a modified C-terminal fragment
  Heffernan MA; Thorburn AW; Fam B; Summers R; Conway-Campbell B; Waters MJ · 2001 · International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity Animal study
• Differing thresholds for modulatory effects of adrenomedullin infusion on haemodynamic and hormonal responses to angiotensin II and adrenocorticotrophic hormone in healthy volunteers
  Troughton RW|Lewis LK|Yandle TG|Richards AM|Nicholls MG · 2001 · Clinical Science Placebo controlled crossover study
• Metabolic studies of a synthetic lipolytic domain of human growth hormone
  Ng FM|et al. · 2000 · Hormone Research Animal study
• A synthetic dipeptide vilon (L-Lys-L-Glu) inhibits growth of spontaneous tumors and increases life span of mice
  Khavinson VK|Mikhailova ON · 2000 · Bulletin of Experimental Biology and Medicine Animal study
• Effects of oral administration of a synthetic fragment of human growth hormone on lipid metabolism
  Heffernan MA, Thorburn AW, Fam B, Summers R, Conway-Campbell B, Waters MJ, Ng FM · 2000 · American Journal of Physiology-Endocrinology and Metabolism Preclinical and ex vivo study
• Thymosin beta4 accelerates wound healing
  Malinda KM, et al. · 1999 · Journal of Investigative Dermatology Animal study
• Pharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide, in human volunteers
  Gobburu JV, Agersø H, Jusko WJ, Ynddal L · 1999 · Pharmaceutical Research Human pharmacology study
• Sermorelin: a review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency
  Prakash A, Goa KL · 1999 · BioDrugs Narrative review
• The amylin analog pramlintide improves glycemic control and reduces postprandial glucagon concentrations in patients with type 1 diabetes mellitus
  Nyholm B|Orskov L|Hove KY|Gravholt CH|Moller N|Alberti KG|Moyses C|Kolterman O|Schmitz O · 1999 · Metabolism Randomized clinical study
• Effectiveness of Semax in the acute period of hemispheric ischemic stroke
  Gusev EI|et al. · 1997 · Zhurnal Nevrologii i Psikhiatrii imeni S.S. Korsakova Small clinical study
• Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor
  Vaughan J|Donaldson C|Bittencourt J|Perrin MH|Lewis K|Sutton S|Chan R|Turnbull AV|Lovejoy D|Rivier C|Rivier J|Sawchenko PE|Vale W · 1995 · Nature Discovery and receptor characterisation
• Growth hormone-releasing peptide-6 stimulates sleep, growth hormone, ACTH and cortisol release in normal man
  Frieboes RM, Murck H, Maier P, Schier T, Holsboer F, Steiger A · 1995 · Neuroendocrinology Controlled human pharmacology study
• Growth hormone-releasing activity of hexarelin in humans
  Imbimbo BP, Mant T, Edwards M, et al. · 1994 · European Journal of Clinical Pharmacology Randomized placebo controlled human pharmacology study
• Effects of delta sleep-inducing peptide on sleep of chronic insomniac patients
  Bes F|et al. · 1992 · Neuropsychobiology Double blind small trial
• Saturable mechanism for delta sleep-inducing peptide (DSIP) at the blood-brain barrier of the vascularly perfused guinea pig brain
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