receptor_pharmacology_review · 2009
VPAC and PAC receptors: from ligands to function
Dickson L|Finlayson K · Pharmacology and Therapeutics
strongPMID · 19109992Verified
Plain-English summary
The review provides the canonical receptor framework for VIP activity at VPAC receptors.
Population
VPAC and PAC receptor literature
Intervention
VIP, PACAP and receptor-selective ligands
Outcomes measured
Receptor pharmacology|Signalling|Physiological function
Key findings
Established VPAC1 and VPAC2 as major receptors for VIP.
Limitations
Narrative review|Therapeutic claims require indication-specific trialsRisk of bias
Low for receptor classification; moderate for therapeutic extrapolation.Citation
Dickson L|Finlayson K (2009). VPAC and PAC receptors: from ligands to function. Pharmacology and Therapeutics
Linked peptides in the PeptiBrief database