Evidence Library
receptor_pharmacology_review · 2009

VPAC and PAC receptors: from ligands to function

Dickson L|Finlayson K · Pharmacology and Therapeutics
strongPMID · 19109992Verified
Plain-English summary

The review provides the canonical receptor framework for VIP activity at VPAC receptors.

Population
VPAC and PAC receptor literature
Intervention
VIP, PACAP and receptor-selective ligands
Outcomes measured
Receptor pharmacology|Signalling|Physiological function
Key findings
Established VPAC1 and VPAC2 as major receptors for VIP.
Limitations
Narrative review|Therapeutic claims require indication-specific trials
Risk of bias
Low for receptor classification; moderate for therapeutic extrapolation.
Citation
Dickson L|Finlayson K (2009). VPAC and PAC receptors: from ligands to function. Pharmacology and Therapeutics
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