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PeptiBrief
Animal combination study· 2017

Peptide Selank Enhances the Effect of Diazepam in Reducing Anxiety in Unpredictable Chronic Mild Stress Conditions in Rats

Kasian A; Kolomin T; Andreeva L; Bondarenko E; Myasoedov N; Slominsky P

Behavioural neurology

DOI
10.1155/2017/5091027
PubMed
28280289
Evidence level
preclinical
Verification
needs_review

Summary

In a rat CMS model, Selank enhances the anxiolytic effect of diazepam. A Selank-alone arm is present per the full text but its independent effect size is modest compared to the combination.

Limitations

Combination-focused design; rat model only; small per-arm groups; behavioural readouts subject to observer bias.

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