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PeptiBrief
Animal gene expression study· 2010

Semax and Pro-Gly-Pro activate the transcription of neurotrophins and their receptor genes after cerebral ischemia

Dmitrieva VG; Povarova OV; Skvortsova VI; Limborska SA; Myasoedov NF; Dergunova LV

Cellular and molecular neurobiology

DOI
10.1007/s10571-009-9432-0
PubMed
19633950
Evidence level
preclinical
Verification
verified

Summary

In rat brain following ischemia, Semax and its Pro-Gly-Pro fragment activated transcription of BDNF, NGF, and their receptor genes.

Limitations

Rat model; transcription-level readout; older methodology.

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