Animal gene expression study· 2020
Novel Insights into the Protective Properties of ACTH((4-7))PGP (Semax) Peptide at the Transcriptome Level Following Cerebral Ischaemia-Reperfusion in Rats
Filippenkov IB; Stavchansky VV; Denisova AE; Yuzhakov VV; Sevan'kaeva LE; Sudarkina OY
Genes
- PubMed
- 32580520
- Evidence level
- preclinical
- Verification
- verified
Summary
In a rat middle-cerebral-artery-occlusion model, Semax administration modulated brain transcriptomic responses to ischemia, notably in immune and neuroprotective pathways.
Limitations
Rat model only; transcriptome-level readout; no functional-recovery endpoint quantified here.