Narrative review· 2018
Thymosin beta 4 and the eye: the journey from bench to bedside
Sosne G
Expert opinion on biological therapy
- PubMed
- 30063853
- Evidence level
- review
- Verification
- needs_review
Summary
Sosne 2018 (Expert Opin Biol Ther) first-person autobiographical review covering the development of thymosin β4 as an ocular-surface therapy from bench to Phase 3 clinical trials in dry-eye disease and neurotrophic keratopathy.
Limitations
Autobiographical/editorial format with strongly promotional tone in the abstract ("thrilling exhilaration", "electrifying possibility"); single-author review; the underlying evidence base is the referenced Phase 3 trials, not this paper itself; not suitable as a stand-alone evidence source.