Human pharmacology study· 1999
Pharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide, in human volunteers
Gobburu JV, Agersø H, Jusko WJ, Ynddal L
Pharmaceutical Research
- PubMed
- 10496658
- Evidence level
- low_to_moderate
- Verification
- verified
Summary
A dose-escalation pharmacokinetic and pharmacodynamic study assessed intravenous ipamorelin and growth hormone responses in healthy volunteers.
Limitations
Small early-phase study with biomarker endpoints and no long-term safety or efficacy assessment.