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Evidence Library
animal_study · 2001

The effects of human GH and its lipolytic fragment AOD9604 on lipid metabolism following chronic treatment in obese mice and beta-3 adrenergic knockout mice

Heffernan MA|et al. · Endocrinology
preclinicalPMID · 11713213Verified
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Plain-English summary

AOD-9604 reduced body weight and fat-related measures in obese mice under experimental conditions.

Population
Obese and beta-3 adrenergic receptor knockout mice
Intervention
AOD-9604
Outcomes measured
Body weight|body fat|lipolysis|fat oxidation
Key findings
Preclinical lipolytic and weight-related effects.
Limitations
Animal findings cannot establish human weight-loss effectiveness or safety.
Risk of bias
Moderate preclinical risk.
Citation
Heffernan MA|et al. (2001). The effects of human GH and its lipolytic fragment AOD9604 on lipid metabolism following chronic treatment in obese mice and beta-3 adrenergic knockout mice. Endocrinology
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