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animal_gene_expression_study · 2014

The peptide Semax affects the expression of genes related to the immune and vascular systems in rat brain focal ischemia

Medvedeva EV|et al. · BMC Genomics
preclinicalVerified
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Plain-English summary

Semax altered expression of immune, vascular and neuroprotective genes after experimental brain ischemia.

Population
Rats with focal cerebral ischemia
Intervention
Semax
Outcomes measured
Brain gene-expression patterns
Key findings
Broad transcriptional effects after experimental ischemia.
Limitations
Animal model|Gene-expression changes do not establish human clinical benefit
Risk of bias
Moderate preclinical risk.
Citation
Medvedeva EV|et al. (2014). The peptide Semax affects the expression of genes related to the immune and vascular systems in rat brain focal ischemia. BMC Genomics
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