Randomized clinical trial· 2021
Effect of vasoactive intestinal polypeptide on development of migraine headaches: a randomized clinical trial
Pellesi L|Al-Karagholi MAM|Chaudhry BA|Snellman J|Hannibal J|Amin FM|Ashina M
JAMA Network Open
- PubMed
- 34357396
- Evidence level
- strong
- Verification
- verified
Summary
A randomized infusion study evaluated whether prolonged VIP exposure provokes migraine attacks.
Limitations
Provocation model|Small specialist sample|Not a therapeutic efficacy trial