Randomized controlled trial· 2015
A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management
Pi-Sunyer X, Astrup A, Fujioka K, et al.
New England Journal of Medicine
- PubMed
- 26132939
- Evidence level
- high
- Verification
- verified
Summary
Randomized double-blind trial of liraglutide 3.0 mg or placebo, alongside diet and exercise, in adults with obesity or overweight and related comorbidity.
Limitations
The study assessed a selected trial population under structured support. Gastrointestinal adverse effects and discontinuation limit generalizability, and longer-term maintenance requires separate evidence.