Randomized placebo controlled trial· 2006

Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults

Teichman SL, Neale A, Lawrence B, Gagnon C, Castaigne JP, Frohman LA

Journal of Clinical Endocrinology and Metabolism

DOI
10.1210/jc.2005-1536
PubMed
16352683
Evidence level
moderate
Verification
verified

Summary

Two randomized, placebo-controlled, double-blind ascending-dose studies evaluated single and repeated subcutaneous CJC-1295 in healthy adults.

Limitations

Healthy volunteers, short follow-up and biomarker endpoints limit conclusions about therapeutic benefit and long-term safety.

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