Randomized placebo controlled trial· 2006
Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults
Teichman SL, Neale A, Lawrence B, Gagnon C, Castaigne JP, Frohman LA
Journal of Clinical Endocrinology and Metabolism
- PubMed
- 16352683
- Evidence level
- moderate
- Verification
- verified
Summary
Two randomized, placebo-controlled, double-blind ascending-dose studies evaluated single and repeated subcutaneous CJC-1295 in healthy adults.
Limitations
Healthy volunteers, short follow-up and biomarker endpoints limit conclusions about therapeutic benefit and long-term safety.