analytical_characterization_study · 2014
Mass spectrometric characterization of a biotechnologically produced full-length mechano growth factor relevant for doping controls
Thevis M, Thomas A, Geyer H, Schänzer W · Growth Hormone and IGF Research
analyticalDOI · 10.1016/j.ghir.2014.10.004PMID · 25466910Verified
Plain-English summary
The study confirms that manufactured MGF-like products can be analytically characterised for anti-doping purposes, but it provides no evidence that PEG-MGF is safe or effective in humans.
Population
Laboratory reference material
Intervention
Mass-spectrometric analysis of biotechnologically produced full-length MGF
Outcomes measured
Molecular characterization|Analytical detection|Anti-doping relevance
Key findings
A manufactured MGF derivative was characterised and incorporated into sports-drug testing approaches.
Limitations
Analytical study without clinical dosing, efficacy or safety outcomes. The characterised material should not be assumed to match all products marketed as PEG-MGF.Risk of bias
Low for analytical characterization but unsuitable for clinical conclusions.Citation
Thevis M, Thomas A, Geyer H, Schänzer W (2014). Mass spectrometric characterization of a biotechnologically produced full-length mechano growth factor relevant for doping controls. Growth Hormone and IGF Research. https://doi.org/10.1016/j.ghir.2014.10.004
Linked peptides in the PeptiBrief database