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PeptiBrief
Cosmetic peptide

Acetyl Tetrapeptide-3

A topical cosmetic hair peptide studied mainly as part of multi-ingredient products. Combination-trial evidence does not establish peptide-specific hair-growth efficacy.

Evidence confidence

Human
2/5
Some human clinical evidence
1 citation
Animal
Not yet assessed
Trust Engine review pending.
Mechanistic
Not yet assessed
Trust Engine review pending — see editorial links below.
Editorial evidence links exist, but this category has not yet completed Trust Engine assessment.
Safety
2/5
Partially characterised safety
1 citation

Claimed uses

Mechanisms

Safety notes

Scalp irritation or sensitisation can occur. Hair loss may reflect medical causes requiring assessment, and evidence does not support replacing established treatments.

Regulation
  • Cosmetic ingredient; not an approved medicine for androgenetic alopecia.

References

  1. An Herbal Extract Combination (Biochanin A, Acetyl tetrapeptide-3, and Ginseng Extracts) versus 3% Minoxidil Solution for the Treatment of Androgenetic Alopecia: A 24-week, Prospective, Randomized, Triple-blind, Controlled Trial · 2020
Last reviewed
11 July 2026
Important PeptiBrief is an educational information platform. It does not diagnose, prescribe, sell peptides, recommend dosing, encourage self-experimentation or replace qualified medical care. Published scientific evidence is kept separate from community observations and uncertainty.