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PeptiBrief
Synthetic tetrapeptide

AEDG Peptide

A synthetic tetrapeptide studied in cell, animal and limited human research for gene regulation, circadian biology and cellular ageing. Clinical evidence is insufficient.

Sequence
Ala-Glu-Asp-Gly
Formula
C15H24N4O9
Molecular weight
404.37 Da

Evidence confidence

Human
Not yet assessed
Trust Engine review pending.
Animal
Not yet assessed
Trust Engine review pending.
Mechanistic
3/5
Multiple mechanistic studies
2 citations
Safety
Not yet assessed
Trust Engine review pending.

Claimed uses

Mechanisms

Safety notes

Long-term safety, carcinogenic risk and consequences of altering telomerase or gene expression are not established. Online products may not match research material.

Regulation
  • Not approved as an anti-ageing, sleep or longevity medicine in major regulated markets.

References

  1. AEDG Peptide (Epitalon) Stimulates Gene Expression and Protein Synthesis during Neurogenesis: Possible Epigenetic Mechanism · 2020
  2. Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells · 2003
Last reviewed
11 July 2026
Important PeptiBrief is an educational information platform. It does not diagnose, prescribe, sell peptides, recommend dosing, encourage self-experimentation or replace qualified medical care. Published scientific evidence is kept separate from community observations and uncertainty.