Endogenous peptide
Angiotensin-(1-7)
An endogenous renin-angiotensin-system peptide with vasodilatory, anti-inflammatory and antifibrotic actions in experimental models. Therapeutic administration remains investigational.
- Sequence
- Asp-Arg-Val-Tyr-Ile-His-Pro
- Formula
- C41H62N12O11
- Molecular weight
- 899.0 Da
Evidence confidence
Human
2/5
Some human clinical evidence
1 citation
Animal
Not yet assessed
Trust Engine review pending.
Mechanistic
Not yet assessed
Trust Engine review pending — see editorial links below.
Editorial evidence links exist, but this category has not yet completed Trust Engine assessment.
Safety
2/5
Partially characterised safety
1 citation
Claimed uses
- Insufficient
Mechanisms
- not-yet-documented
- Nitric oxide / blood flow
- Inflammation modulation
Safety notes
Potential risks include hypotension, dizziness and unpredictable interaction with renin-angiotensin-system medicines. Long-term dosing and product quality are not established.
Regulation
- Not approved as a general cardiovascular, renal, pulmonary or performance medicine.
References
Last reviewed
11 July 2026