Drug class or analogue

ANP Analogue

A class of engineered natriuretic peptides designed to activate guanylyl cyclase-A and promote vasodilation, natriuresis and blood-pressure reduction.

Evidence confidence

Human
2/5
Some human clinical evidence
1 citation
Animal
Not yet assessed
Trust Engine review pending.
Mechanistic
Not yet assessed
Trust Engine review pending — see editorial links below.
Editorial evidence links exist, but this category has not yet completed Trust Engine assessment.
Safety
Not yet assessed
Trust Engine review pending.

Claimed uses

Mechanisms

Safety notes

Possible risks include hypotension, dizziness, syncope, altered renal perfusion and electrolyte or fluid changes. Safety cannot be generalised across analogues.

Regulation
  • No general ANP analogue class approval. Individual products may be investigational or licensed only for specific jurisdictions and indications.

References

  1. First-in-Human Study of MANP: A Novel ANP (Atrial Natriuretic Peptide) Analog in Human Hypertension · 2021
Last reviewed
11 July 2026
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