Endogenous peptide hormone
Atrial Natriuretic Peptide
An endogenous cardiac peptide that promotes natriuresis, vasodilation and suppression of the renin-aldosterone system.
- Sequence
- SLRRSSCFGGRIDRIGAQSGLGCNSFRY
- Formula
- C127H203N45O39S3
- Molecular weight
- 3080.5 Da
Evidence confidence
Human
Not yet assessed
Trust Engine review pending.
Animal
Not yet assessed
Trust Engine review pending.
Mechanistic
Not yet assessed
Trust Engine review pending — see editorial links below.
Editorial evidence links exist, but this category has not yet completed Trust Engine assessment.
Safety
Not yet assessed
Trust Engine review pending.
Claimed uses
- Insufficient
Mechanisms
- not-yet-documented
- Natriuretic peptide receptor-A signalling
- Nitric oxide / blood flow
Safety notes
Exogenous ANP can cause hypotension, dizziness, altered renal function and fluid or electrolyte disturbances. Medical monitoring is required.
Regulation
- Therapeutic availability and approval vary by jurisdiction; not approved for general wellness, weight loss or performance use.
References
Last reviewed
12 July 2026