Research peptide
MGF
MGF is a research peptide indexed in the PeptiBrief evidence database.
Evidence confidence
Human
Not yet assessed
Trust Engine review pending.
Animal
Not yet assessed
Trust Engine review pending.
Mechanistic
3/5
Multiple mechanistic studies
2 citations
Safety
Not yet assessed
Trust Engine review pending.
Claimed uses
- Insufficient
- Insufficient
Mechanisms
- not-yet-documented
- MGF E-domain cell response
- IGF-1 receptor signalling
Safety notes
Long-term safety, validated dosing and product quality may be uncertain outside formal clinical development.
Regulation
- Not approved as a human medicine and prohibited in sport under growth-factor and related-substance rules.
- Not approved for general wellness or performance use unless a specific regulated product and indication exists.
References
- Mechano-growth factor peptide, the COOH terminus of unprocessed insulin-like growth factor 1, has no apparent effect on myoblasts or primary muscle stem cells · 2014
- Mechano Growth Factor E peptide, derived from an isoform of IGF-1, activates human muscle progenitor cells and induces an increase in their fusion potential at different ages · 2011
Last reviewed
12 July 2026