Peptide medicine

Semaglutide

Semaglutide is a regulated peptide medicine with established evidence in defined indications.

Formula
C187H291N45O59
Molecular weight
4113.58 g/mol

Evidence confidence

Human
2/5
Some human clinical evidence
1 citation
Animal
Not yet assessed
Trust Engine review pending.
Mechanistic
Not yet assessed
Trust Engine review pending — see editorial links below.
Editorial evidence links exist, but this category has not yet completed Trust Engine assessment.
Safety
2/5
Partially characterised safety
1 citation

Claimed uses

Mechanisms

Safety notes

Adverse effects, contraindications and monitoring requirements depend on the approved formulation and indication.

Regulation
  • Approved prescription medicine in multiple jurisdictions. Brand, formulation, dose and authorised indication vary; compounded or counterfeit products are not equivalent to authorised medicines.
  • Prescription or regulated medicine with jurisdiction-specific indications.

References

  1. Once-Weekly Semaglutide in Adults with Overweight or Obesity · 2021
Last reviewed
12 July 2026
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