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Evidence Library
animal_lifespan_study · 2003

Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice

Anisimov VN|et al. · Biogerontology
preclinicalPMID · 14501183Verified
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Plain-English summary

Epitalon did not increase mean lifespan in this mouse study, although some other ageing-related outcomes were reported.

Population
Female SHR mice
Intervention
Repeated Epitalon administration
Outcomes measured
Mean lifespan|ageing biomarkers|tumour incidence
Key findings
No increase in mean lifespan.
Limitations
Single mouse strain|Animal study|Findings may not translate to humans
Risk of bias
Moderate preclinical risk.
Citation
Anisimov VN|et al. (2003). Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice. Biogerontology
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