Randomized crossover study· 2024
Cardiovascular and renal effects of apelin in chronic kidney disease
Chapman FA|Nyimanu D|Maguire JJ|Davenport AP|Webb DJ|Newby DE
Kidney International
- PubMed
- 39402039
- Evidence level
- moderate
- Verification
- verified
Summary
A placebo-controlled crossover study evaluated pyr-apelin-13 in healthy participants and people with chronic kidney disease.
Limitations
Acute infusion|Small clinical study|No long-term outcomes|Specific stabilized endogenous isoform