Narrative review· 2009

Delta sleep-inducing peptide and glucocorticoid-induced leucine zipper: potential links between circadian mechanisms and obesity?

Gimble JM; Ptitsyn AA; Goh BC; Hebert T; Yu G; Wu X

Obesity reviews : an official journal of the International Association for the Study of Obesity

DOI
10.1111/j.1467-789X.2009.00661.x
PubMed
19849801
Evidence level
review
Verification
needs_review

Summary

Gimble et al. 2009 review of circadian-adipose links proposing the 'DSIP-immunoreactor' — also referred to as glucocorticoid-induced leucine zipper (GILZ) — as a candidate node between circadian biology and adipose metabolism.

Limitations

Narrative review; discussion frame explicitly conflates 'DSIP-like immunoreactor' with GILZ (a distinct protein product) rather than with the DSIP peptide itself; identity risk on the DSIP slug.

Linked peptides

Important PeptiBrief is an educational information platform. It does not diagnose, prescribe, sell peptides, recommend dosing, encourage self-experimentation or replace qualified medical care. Published scientific evidence is kept separate from community observations and uncertainty.