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PeptiBrief
Research peptide

DSIP

DSIP is a research peptide indexed in the PeptiBrief evidence database. It has a defined amino-acid sequence in this dossier.

Sequence
WAGGDASGE

Evidence confidence

Human
3/5
Multiple human studies
2 citations
Animal
2/5
Some animal evidence
1 citation
Mechanistic
Not yet assessed
Trust Engine review pending — see editorial links below.
Editorial evidence links exist, but this category has not yet completed Trust Engine assessment.
Safety
3/5
Reasonable safety characterisation
2 citations

Claimed uses

Mechanisms

Safety notes

Long-term safety, validated dosing and product quality may be uncertain outside formal clinical development.

Regulation
  • Not generally licensed as a medicine for insomnia in the United States or United Kingdom.
  • Not approved for general wellness or performance use unless a specific regulated product and indication exists.

References

  1. Delta sleep-inducing peptide: a still unresolved riddle · 2006
  2. Effects of delta sleep-inducing peptide on sleep of chronic insomniac patients · 1992
  3. Saturable mechanism for delta sleep-inducing peptide (DSIP) at the blood-brain barrier of the vascularly perfused guinea pig brain · 1989
  4. Delta sleep-inducing peptide (DSIP)-like immunoreactivity in gut: coexistence with known peptide hormones · 1989
  5. Potent antinociceptive effect of centrally administered delta-sleep-inducing peptide (DSIP) · 1988
  6. Effects of DSIP in man: multifunctional psychophysiological properties · 1983
Last reviewed
12 July 2026
Important PeptiBrief is an educational information platform. It does not diagnose, prescribe, sell peptides, recommend dosing, encourage self-experimentation or replace qualified medical care. Published scientific evidence is kept separate from community observations and uncertainty.