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PeptiBrief
Tissue immunohistochemistry study· 1989

Delta sleep-inducing peptide (DSIP)-like immunoreactivity in gut: coexistence with known peptide hormones

Bjartell A; Ekman R; Hedenbro J; Sjölund K; Sundler F

Peptides

DOI
10.1016/0196-9781(89)90093-4
PubMed
2664725
Evidence level
laboratory
Verification
verified

Summary

Bjartell et al. 1989 report that DSIP-like immunoreactivity is present in gut endocrine cells (gastrin/CCK, secretin, PYY/glicentin) in humans, pigs and rats — with the highest concentrations in human specimens — and that HPLC of gut extracts shows a single DSIP-like peak with the retention time of DSIP 3-9.

Limitations

Tissue-localisation study only; no interventional or clinical outcome; older methodology (1989); immunoreactivity ≠ confirmed intact DSIP presence (antibody cross-reactivity possible).

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