Observational pilot study· 2025
MOTS-c Levels and Sarcopenia Risk in Chronic Peritoneal Dialysis Patients: A Pilot Study
Zicarelli M; Greco M; Roumeliotis S; Lo Vasco ME; Dragone F; Kourtidou C
Medicina (Kaunas, Lithuania)
- PubMed
- 40005438
- Evidence level
- low
- Verification
- verified
Summary
Observational pilot in 32 peritoneal-dialysis patients: those at higher sarcopenia risk had lower serum and higher dialysate MOTS-c, suggesting altered peritoneal clearance. Biomarker-association only; no intervention.
Limitations
Very small n=32; single-center; observational (no MOTS-c administered); sarcopenia risk measured by SARC-F rather than gold-standard tools; wide confidence intervals.