narrative_review · 2020
Current perspective on a peptide hormone with significant therapeutic potential
Fischer JP|Els-Heindl S|Beck-Sickinger AG · Peptides
moderateDOI · 10.1016/j.peptides.2020.170322PMID · 32569606Verified
Plain-English summary
Adrenomedullin is an endogenous 52-amino-acid hormone involved in vascular, lymphatic and inflammatory regulation, but therapeutic use remains investigational.
Population
Preclinical and human adrenomedullin literature
Intervention
Adrenomedullin and related receptor-targeting strategies
Outcomes measured
Vascular tone|Endothelial barrier function|Lymphatic biology|Therapeutic development
Key findings
Supports established physiological activity and investigational therapeutic potential.
Limitations
Narrative review|Therapeutic applications remain experimental|Does not establish safety of unregulated peptide productsRisk of bias
Moderate — broad peer-reviewed synthesis without systematic-review methods.Citation
Fischer JP|Els-Heindl S|Beck-Sickinger AG (2020). Current perspective on a peptide hormone with significant therapeutic potential. Peptides. https://doi.org/10.1016/j.peptides.2020.170322
Linked peptides in the PeptiBrief database