In vitro reproducibility study· 2014

Mechano-growth factor peptide, the COOH terminus of unprocessed insulin-like growth factor 1, has no apparent effect on myoblasts or primary muscle stem cells

Fornaro M, Hinken AC, Needle S, et al.

American Journal of Physiology-Endocrinology and Metabolism

PubMed
24253050
Evidence level
laboratory
Verification
verified

Summary

Independent laboratory evaluation of native and stabilised synthetic MGF peptides in mouse and human muscle-cell systems.

Limitations

Laboratory systems cannot exclude every possible tissue context, formulation or delivery effect, but directly challenge prominent mechanistic claims.

Linked peptides

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