Narrative review· 2020
From Angiotensin IV to Small Peptidemimetics Inhibiting Insulin-Regulated Aminopeptidase
Hallberg M|Nyberg F
Frontiers in Pharmacology
- PubMed
- 33178027
- Evidence level
- moderate
- Verification
- verified
Summary
Review of angiotensin IV, the AT4 binding site and insulin-regulated aminopeptidase inhibitor development.
Limitations
Narrative review|Evidence is mainly preclinical|Native peptide has poor drug-like properties|No established human treatment