In vitro human cell study· 2011

Mechano Growth Factor E peptide, derived from an isoform of IGF-1, activates human muscle progenitor cells and induces an increase in their fusion potential at different ages

Kandalla PK, Goldspink G, Butler-Browne G, Mouly V

Mechanisms of Ageing and Development

DOI
10.1016/j.mad.2011.02.007
PubMed
21354439
Evidence level
laboratory
Verification
verified

Summary

Study of synthetic MGF E-domain peptide in cultured human muscle progenitor cells obtained from donors of different ages.

Limitations

In vitro design, limited donor samples, uncertain translation to intact human tissue and later reproducibility concerns.

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