Discovery and animal study· 2008

Identification of adropin as a secreted factor linking dietary macronutrient intake with energy homeostasis and lipid metabolism

Kumar KG|Trevaskis JL|Lam DD|Sutton GM|Koza RA|Chouljenko VN|Kousoulas KG|Rogers PM|Kesterson RA|Thearle M|Ferrante AW Jr|Mynatt RL|Burris TP|Dong JZ|Halem HA|Culler MD|Heisler LK|Stephens JM|Butler AA

Cell Metabolism

DOI
10.1016/j.cmet.2008.10.011
PubMed
19041763
Evidence level
preclinical
Verification
verified

Summary

The original discovery study identified adropin as an ENHO-encoded peptide involved in energy homeostasis.

Limitations

Predominantly animal and mechanistic work|Does not establish therapeutic efficacy or dosing in humans

Linked peptides

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