Discovery and animal study· 2008
Identification of adropin as a secreted factor linking dietary macronutrient intake with energy homeostasis and lipid metabolism
Kumar KG|Trevaskis JL|Lam DD|Sutton GM|Koza RA|Chouljenko VN|Kousoulas KG|Rogers PM|Kesterson RA|Thearle M|Ferrante AW Jr|Mynatt RL|Burris TP|Dong JZ|Halem HA|Culler MD|Heisler LK|Stephens JM|Butler AA
Cell Metabolism
- PubMed
- 19041763
- Evidence level
- preclinical
- Verification
- verified
Summary
The original discovery study identified adropin as an ENHO-encoded peptide involved in energy homeostasis.
Limitations
Predominantly animal and mechanistic work|Does not establish therapeutic efficacy or dosing in humans