Animal and cell study· 2015

The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance

Lee C|et al.

Cell Metabolism

DOI
10.1016/j.cmet.2015.02.009
PubMed
25738459
Evidence level
preclinical
Verification
verified

Summary

Foundational study identifying MOTS-c and examining metabolic effects.

Limitations

Predominantly cell and mouse evidence|Does not establish injected treatment benefit in humans

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