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PeptiBrief
Evidence Library
narrative_review · 2006

Natriuretic peptides: their structures, receptors, physiologic functions and therapeutic applications

Potter LR|Abbey-Hosch S|Dickey DM · Handbook of Experimental Pharmacology
strongDOI · 10.1007/3-540-32967-6_14PMID · 17087170Verified
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Plain-English summary

ANP is a cardiac hormone that promotes sodium excretion and vasodilation through guanylyl cyclase-A signalling.

Population
Natriuretic peptide literature
Intervention
ANP, BNP, CNP and receptor pathways
Outcomes measured
Receptor biology|Natriuresis|Vasodilation|Clinical applications
Key findings
Established the canonical physiological framework for ANP.
Limitations
Narrative review|Older therapeutic landscape|Does not justify unregulated peptide administration
Risk of bias
Low for core physiology; moderate for therapeutic extrapolation.
Citation
Potter LR|Abbey-Hosch S|Dickey DM (2006). Natriuretic peptides: their structures, receptors, physiologic functions and therapeutic applications. Handbook of Experimental Pharmacology. https://doi.org/10.1007/3-540-32967-6_14
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