Hair Biology
Extracellular-matrix and hair-follicle support
Modulation of perifollicular extracellular-matrix proteins and signalling associated with follicle anchoring and hair growth.
Biological pathway
Acetyl tetrapeptide-3 is marketed as a laminin- and extracellular-matrix-supporting peptide and has been studied within multi-ingredient hair-loss formulations.
Evidence summary
A small randomized trial of a combination containing acetyl tetrapeptide-3 reported hair-density improvement.
Limitations
The peptide contribution cannot be isolated from biochanin A, ginseng extracts and the complete formulation.