Tissue Repair
Extracellular matrix remodelling
Regulation of collagen, elastin, proteoglycans and matrix-degrading enzymes during repair and ageing.
Biological pathway
Fibroblast activity, collagen synthesis and matrix metalloproteinase regulation reshape tissue extracellular matrix.
Evidence summary
GHK-Cu and several repair peptides have laboratory and animal evidence affecting matrix biology.
Limitations
Mechanistic changes do not automatically translate into meaningful clinical outcomes.