Dermatology

Vascular permeability and fluid-balance modulation

Proposed modulation of vascular permeability, capillary integrity and extracellular fluid accumulation in peri-orbital skin.

Biological pathway

Cosmetic claims for acetyl tetrapeptide-5 include reduced glycation and oedema-related fluid retention.

Evidence summary

Published peptide-specific clinical evidence is sparse and largely formulation- or supplier-associated.

Limitations

Mechanism and efficacy remain insufficiently confirmed by independent controlled studies.

Peptides linked to this mechanism

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